Autonomous Devices for Sensing and Release (ADSR)

Assembling biomedical systems for diagnosis and therapy (ADSR)

The purpose of this project is to detect different diseases relevant to today's society, alleviate their symptoms by releasing drugs in a controlled manner, and operate in an energetically autonomous way. The pathologies selected for this project are neuronal (Parkinson's, schizophrenia and amyotrophic lateral sclerosis) for which we will monitor the levels of dopamine (DA), serotonin and gamma-amino butyric acid, diabetes for which we will detect the glucose level (GLU), and the formation of "biofilms" for which we will to discriminate between prokaryotic (bacteria) and eukaryotic cells. The drugs needed to mitigate these diseases are the neurotransmitters whose concentrations are lower than the proper ones, insulin and antibiotics. 

Agency: Secretaría de Estado de Universidades, Investigación, Desarrollo e Innovación; Agencia Estatal de la Investigación (RTI2018-098951-B-I00).

Principal investigator: Prof. Carlos Alemán.

Polycaprolactone microfibers loaded with poly(3,4-ethylenedioxythiophene) nanoparticles and curcumine for controlled drug delivery through an electromechanical mechanism.