COSTA
Improving Multifunctional Electro-responsive Bioplatforms by the Optimization of their Core Elements: COmposition, STructure and Attributes (COSTA)
The COSTA project aims at developing advanced and optimized multifunctional biomedical platforms to promote tissue regeneration, release drugs and monitor bioanalytes in real time (in particular, those that allow the detection of bacterial infections while identifying the pathogen causing them) using electrical stimuli. The smart bioplatforms developed in COSTA, which overcome the shortcomings detected in current bioplatforms and go significantly beyond the present state of the art, will be used for skin would healing, cardiac tissue regeneration and skeletal muscle tissue therapy.
Agency: Agencia Estatal De Investigacion PID2024-157506OB-I00

Principal Investigator: Carlos Alemán and Maria del Mar Pérez Madrigal
PhD Students:Maria Dolores Ramirez Alba, Marc Arnau Roca, Júlia Sanz Farnós, Alvaro Hidalgo Yerga, Isabel Teixido, Marta Villa Moreno, Zarghona Shazmeen, Alejandra Sanchez Sanz
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Optimizing electro-responsive glyoxal-crosslinked alginate hydrogel for the electrochemical detection of NADH and antibacterial activity in smart dressing biointerfaces
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International journal of biological macromolecules
Vol. 371 num. article 153047
DOI: 10.1016/j.ijbiomac.2026.153047
Data de publicació: 07/2026
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Three-dimensional magnetoelectric nanocomposite GelMA hydrogels for wireless electrical stimulation of cardiac cells
Ángel Viteri; Vargas, C.; Colombi, S.; Resina, L.; Tan, H.; Julia, J.; Ginebra, M.P.; Engel, E.; Aleman, C.; Garcia-Torres, J.
ACS Applied materials and interfaces
Vol. 18 num. 19 p. 28020-28032
DOI: 10.1021/acsami.6c05467
Data de publicació: 07/05/2026
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Electroresponsive hydrogel for wound healing with real-time monitoring of bacterial NADH to prevent infection
Castrejon, V.; Zanuy, D.; Fontana, A.; Resina, L.; Perez, M.; Aleman, C.
ACS applied polymer materials
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DOI: 10.1021/acsapm.5c04585
Data de publicació: 11/03/2026
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